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Rate-Controlled Administration IV push is possible for glutathione, but slower infusion allows better cellular uptake and reduces the risk of sulfur-related reactions (temporary garlic odor in breath harmless but manageable with slow administration)

Potential concerns include effects on angiogenesis that theoretically could influence tumor development or progression, though preclinical studies show context-dependent effects that inhibit pathological angiogenesis in some tumor models

doi: 10.1016/j.clinre.2012.06.006 69 CanyellesMTondoMCedLFarrsMEscol-GilJCBlanco-VacaF

Citations [1] Mikus D, Sikiric P, Seiwerth S, Petricevic A, Aralica G, Druzijancic N, Rucman R, Petek M, Pigac B, Perovic D, Kolombo M, Kokic N, Mikus S, Duplancic B, Fattorini I, Turkovic B, Rotkvic I, Mise S, Prkacin I, Konjevoda P, Stambuk N, Anic T